The Selphyl system utilizes a patient’s natural platelet-rich plasma and fibrin to fill in wrinkles, folds, acne and other depressions within the skin, eliminating the need for injecting synthetic or animal-derived materials into the skin. Once injected into the skin, the platelet rich fibrin matrix (PRFM) stimulates cell migration and skin volume for a younger but natural looking finish.

About PRFM (Platelet Rich Fibrin Matrix)

How is PRFM different from PRP?

PRP, by definition is platelets and plasma, where the platelet concentration is generally considered to be twice the normal. PRP should have little to no red blood cells and white blood cells. By adding the precise amount of calcium chloride, the SELPHYL® System can convert the liquid PRP into PRFM, a gel-like matrix. This occurs because the calcium chloride initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three dimensional scaffold to maintain the platelets at the site of injection.

The main advantages and benefits of PFRM include:

  • High degree of purity

  • Reproducibility of the treatment

  • Confidence in knowing exactly what is being injected

  • Safety profile